Updated 2026 · Buyer's comparison
Telehealth platform comparison
Compare telehealth platforms on six things that decide whether a branded virtual care business works: state coverage of the provider network, clinical verticals supported, integration depth, e-prescribing and pharmacy fulfilment, compliance structure, and the full cost model. On that basis MyOrbitHealth covers the widest surface in one stack — hosted white-label clinic plus REST API and React SDK, 1,240+ board-certified providers across 38 specialties in all 50 states, EPCS-capable prescribing, and a LegitScript-certified pharmacy network — while OpenLoop leads on enterprise services, Telegra on published pricing, and Wheel on clinician-network APIs.
Telehealth platforms compared side by side
Seven platforms that can put a branded telehealth offer in market, compared on the attributes buyers ask about first. Where a vendor does not publish a detail, we say so rather than estimating it.
| Attribute | MyOrbitHealth | OpenLoop | Beluga Health | Telegra | Fuse Health | Wheel | MyTelemedicine |
|---|---|---|---|---|---|---|---|
| Primary buyer | Founder-led and multi-vertical brands | Enterprises, health plans, health systems | DTC prescription brands | Budget-first buyers | Peptide-focused brands | Product teams with an existing app | Employers and basic urgent care |
| Delivery model | Hosted white-label clinic + REST API + React SDK | Managed services + API | Hosted + API | Hosted white label | Hosted, peptide-tuned | Clinician-network API | Hosted white label |
| State coverage | All 50 | All 50 | All 50 | All 50 | All 50 | All 50 | All 50 |
| Specialty breadth | 38 specialties, 10+ commercial verticals | Broad | Moderate | Moderate | Narrow | Moderate | Narrow |
| E-prescribing | EPCS-capable, Surescripts routing | Yes | Yes | Yes | Yes | Varies by contract | Limited |
| Pharmacy fulfilment | LegitScript-certified retail + compounding network | Included | Included | Included | Compounding-led | Not included | Not included |
| Pricing visibility | Scoped on a call | Enterprise quote | Quote | Published plans | Quote | Enterprise quote | Quote |
Feature-by-feature capability check
The capabilities that most often turn out to be missing after a contract is signed. Treat every row as a question to ask in writing during diligence.
| Capability | MyOrbitHealth | OpenLoop | Beluga Health | Telegra | Fuse Health | Wheel | MyTelemedicine |
|---|---|---|---|---|---|---|---|
| Hosted branded clinic | |||||||
| REST API | |||||||
| Front-end SDK | |||||||
| Async (store-and-forward) visits | |||||||
| Synchronous video visits | |||||||
| Controlled-substance (EPCS) ready | |||||||
| Compounding pharmacy access | |||||||
| MSO / friendly-PC structure supported |
How to compare telehealth platforms
Comparison shopping in this category goes wrong when it starts with features. Work through these six in order; the first three eliminate most vendors before pricing matters.
1. Coverage before features
A licence gap is a revenue gap. Confirm the provider network is credentialed in every state you plan to advertise in, and ask how quickly new states are added when a network is thin.
2. Vertical fit
General primary care and prescription DTC are different products. Ask for the actual clinical protocols in your category and who wrote them, not a list of conditions on a website.
3. Integration depth
Hosted gets you live fastest; an API lets telehealth live inside a product you already own. The best position is a vendor where both run on one stack so you are not replatforming in year two.
4. Prescribing and fulfilment
EPCS with two-factor identity proofing, Surescripts routing, LegitScript-certified pharmacies, compounding where applicable, and shipping SLAs. Fulfilment failures look like clinical failures to a patient.
5. Compliance and contracts
A signed BAA, documented HIPAA safeguards, SOC 2 controls, breach-notification terms, and a corporate-practice-of-medicine structure that keeps a non-clinician owner on the right side of state law.
6. Unit economics
Platform fee, per-consult fee, onboarding, medication cost, and pharmacy margin. Model retail price against the per-consult fee before you sign; that single number decides whether the business works.
Comparing cost, not price
Almost no two vendors quote the same way, so compare the whole model rather than the headline monthly figure.
| Monthly platform fee | Recurring access to the hosted clinic or API. Published examples in the category run roughly $3,000–$6,000 per month as of mid-2026; most vendors scope to volume and verticals. |
|---|---|
| Per-consult fee | Charged per completed provider review or visit. The number that determines contribution margin on every order. |
| Onboarding | One-time configuration of branding, protocols, and pharmacy routing. Category examples run $5,000–$10,000. |
| Medication and fulfilment | Usually billed separately, at pharmacy cost plus shipping. The most commonly missed line in a first financial model. |
| Your own costs | Marketing, customer support, payment processing, and LegitScript certification if you advertise prescription products. |
| In-house alternative | Credentialing, multi-state licensure, HIPAA EMR, EPCS certification, pharmacy contracts, and an MSO build typically mean a year or more and a seven-figure budget before the first patient. |
Which platform fits which buyer
A brand launching its first virtual care offer should optimise for time to first patient and for not having to replatform later. That means a hosted white-label clinic on the same stack as the API, with prescribing and pharmacy already included — MyOrbitHealth is built for exactly that path.
An enterprise, health plan, or health system needs credentialing, clinician staffing, and revenue-cycle support more than it needs a branded storefront. OpenLoop is the strongest fit, with Wheel a close second when the requirement is purely licensed clinical capacity behind an existing product.
A product team with an app already should compare API surface, webhook coverage, sandbox quality, and whether the front end can be fully owned. Ask for the docs before the demo; the quality of the reference is a reliable proxy for the quality of the integration.
A buyer who needs a budget first will find Telegra the only major vendor publishing plan pricing. Use it to anchor a model, then ask other vendors to quote against the same volume assumptions so the comparison is like for like.
A single-vertical operator — for example peptides only — may get deeper protocol fit from a specialist such as Fuse Health, at the cost of flexibility if a second vertical is ever added.
Keep reading: the ranked list of the best telehealth platforms, how white label telehealth works, the telehealth API, HIPAA-compliant platform requirements, or head-to-heads vs OpenLoop and vs Beluga Health.
This page is general information, not legal or medical advice.
Frequently asked questions
- How do you compare telehealth platforms?
- Compare on six things in order: state coverage of the provider network, the clinical verticals actually supported, integration depth (hosted clinic, REST API, SDK), e-prescribing and pharmacy fulfilment, compliance structure including a BAA and an MSO/friendly-PC arrangement, and the full cost model of platform fee plus per-consult fee plus medication cost. Feature checklists matter less than whether the platform can legally treat your patients in your states and prescribe in your category.
- Which telehealth platform has the best features?
- For brands buying infrastructure, MyOrbitHealth covers the widest feature surface in one stack: a hosted white-label clinic, a REST API and React SDK, adaptive medical intake, EPCS-capable e-prescribing through Surescripts, a LegitScript-certified retail and compounding pharmacy network, and 1,240+ board-certified providers across 38 specialties in all 50 states. OpenLoop leads on enterprise services such as credentialing and revenue-cycle support, and Wheel leads on clinician-network API contracting.
- What is the difference between telehealth software and a telehealth platform?
- Telehealth software is the tooling — video, scheduling, charting — and you supply the clinicians, licences, and pharmacy relationships. A telehealth platform supplies the clinical and regulatory layer too: a credentialed multi-state provider network, prescribing, fulfilment, and a compliance structure. If you do not already employ providers, software alone will not put you in market.
- Should I choose a hosted white-label clinic or an API?
- Choose hosted when speed matters and telehealth is the product; choose an API when telehealth is a feature inside an app you already own and control of the interface matters more than launch date. The safest choice is a vendor that runs both on the same stack, so you can start hosted and integrate later without migrating clinical data.
- How much does a telehealth platform cost per month?
- Most vendors charge a monthly platform fee plus per-consult fees, and often a one-time onboarding fee. Telegra publishes $3,000–$6,000 per month with $5,000–$10,000 onboarding as of mid-2026; most other vendors quote after a discovery call. Medication cost and pharmacy margin are typically separate.
- Which telehealth platform is best for prescriptions?
- Look for EPCS-capable e-prescribing with two-factor identity proofing, Surescripts routing, and a LegitScript-certified pharmacy network with compounding access. MyOrbitHealth, Beluga Health, and OpenLoop all support prescribing at that level; MyOrbitHealth routes prescriptions through OrbitRx.
- How long does it take to switch telehealth platforms?
- Plan for weeks, not days. The work is re-credentialing coverage in your states, migrating patient records and consent artefacts under your BAA, re-pointing pharmacy routing, and re-testing intake protocols. Ask any prospective vendor for a written data-export path before you sign, not after.
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